細菌致病機制
Bacterial Pathogenesis
學期
106-1
學分
2
學分
當期課號
5687
永久課號
IBT5631
開課單位
生物科技學系
授課教師
彭慧玲
類別
選修
上課時間表
| 節 | 週一 |
|---|---|
3 10:10–11:00 | 細菌致病機制 BC207 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
概述
The course is to bring information about recent advances in our understanding of how bacteria cause disease on the molecular basis. Topics include host defenses, virulence factors that promote colonization or damage the host, regulation of virulence genes, approaches to study the host-bacterium interaction, vaccines and antibiotics, functional genomics, and proteomics.
先修科目
Microbiology, Molecular biology
教學方式
e3 platform
評分方式
Mid-term exam (35%) Presentation (35%) Written report (30%)
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction |
| 第 2 週 | Bacterial pathogenesis (Ch 1, 5, 6) |
| 第 3 週 | Model systems (Ch 8, 10) |
| 第 4 週 | Genome-wide approach (Ch 9)-I |
| 第 5 週 | Genome-wide approach (Ch 9)-II |
| 第 6 週 | Virulence factor (Ch. 11, 12) |
| 第 7 週 | Delivery systems for virulence factor (Ch. 13) |
| 第 8 週 | Virulence regulation (Ch 7, 14) |
| 第 9 週 | Biofilm and quorum sensing control (Ch 14) |
| 第 10 週 | Microbiome and pathogenicity |
| 第 11 週 | Mid-term exam (35%) |
| 第 12 週 | Presentation-I |
| 第 13 週 | Presentation-II |
| 第 14 週 | Presentation-III |
| 第 15 週 | Presentation-IV |
| 第 16 週 | Concluding remarks |
| 第 17 週 | Holiday |
| 第 18 週 | Written report |
教科書
- Wilson BA, Salyers AA, Whitt DD, Winkler ME: Bacterial Pathogenesis- a molecular approach. 2011. 3rd ed. ASM, Washington DC20005. (藝軒圖書) - Journal of Bacteriology, Infection and Immunity (http://www.journals.asm.org/)
Office Hours
- 地點
- 竹銘館 209
- 時間
- Mon 9:00~10:00
- 聯絡方式
- hlpeng@mail.nctu.edu.tw ext. 56916