生物物理學
Biophysics
學期
107-1
學分
3
學分
當期課號
5419
永久課號
IOP5476
開課單位
物理研究所
授課教師
張正宏
校區
光復
類別
選修
上課時間表
| 節 | 週一 |
|---|---|
5 13:20–14:10 | 生物物理學 SC157 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
概述
Cells can sense their environment, process information, and respond accordingly, which range from the expression of genes to the control of cellular movement. Cells exist in the physical world and follow its laws. In this course, we will use this fundamental biological unit to introduce biophysics. The materials in this course will be based on the structure of the book of Endres. Further mathematical and physical tools will be introduced as supplemental materials.
先修科目
General Physics
教學方式
ppt presentation + black board
評分方式
Two exams (50% + 50%)
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1: Introduction |
| 第 2 週 | 2: Chemotaxis in bacterium Escherichia coli |
| 第 3 週 | holiday |
| 第 4 週 | 3: Physical concepts |
| 第 5 週 | 4: Mathematical tools |
| 第 6 週 | 5: Signal amplification and integration |
| 第 7 週 | 6: Robust precise adaptation |
| 第 8 週 | 7: Polar receptor localization and clustering |
| 第 9 週 | mid-term exam |
| 第 10 週 | 8: Accuracy of sensing |
| 第 11 週 | 9: Motor impulse response |
| 第 12 週 | 10: Optimization of pathway |
| 第 13 週 | 11: 'Seeing' like a bacterium |
| 第 14 週 | 12: Beyond E. coli chemotaxis |
| 第 15 週 | 13: Stochastic Thermodynamics |
| 第 16 週 | 14: Fluctuation-dissipation theory |
| 第 17 週 | 15: Stochastic process |
| 第 18 週 | holiday |
| 第 19 週 | final exam |
教科書
Physical Principles in Sensing and Signaing With an Introduction to Modeling in Biology Robert G. Endres, Oxford University Press (2013)
Office Hours
- 地點
- my office SC414
- 時間
- Thu: 13:00-14:00
- 聯絡方式
- chchang@mail.nctu.edu.tw