生物統計

Biostatistics

學期

108-1

學分

3 學分

當期課號

5415

永久課號

IST5534

開課單位

統計學研究所

授課教師

黃冠華

類別

選修

上課時間表

節	週一
2 09:00–09:50	生物統計 A406 3 節連堂
3 10:10–11:00
4 11:10–12:00

* 根據陽明交大上課時間表所列

概述

This course will cover statistical methods for design, conduct, and analysis of epidemiologic studies such as case-control and cohort studies. Topics include overview of designs for research studies; epidemiologic study design; rates and risk; measures of association; classical contingency table methods; logistic and Poisson regression; and proportional hazard regression. Examples from the literature and data from a number of well-known epidemiologic studies will be used for illustration of the concepts involved.

先修科目

Students are expected to be familiar with basic epidemiologic concepts.

教學方式

Class website: http://ghuang.stat.nctu.edu.tw/course/biostat19/

評分方式

作業部份: There are four homework assignments. 考試部份: One midterm exam and one final exam. 評量部份: The course grade will be based on four homework assignments (40%), one midterm exam (25%), and one final exam (35%).

課程大綱

Introduction and overview of goals of epidemiologic research and epidemiologic study designs
Measures of disease occurrence and association
Control of extraneous factors
Logistic regression
Confounding and interaction in logistic regression
Logistic regression for contingency tables
Logistic regression for case-control and matched data
Poisson regression for count data
Analysis of survival data
Proportional hazards model

教科書

Handouts corresponding to each lecture will be available on the class website before each class. There is no required textbook for this course. Following books are recommended for further reading: Nicholas P. Jewell (2003). Statistics for Epidemiology. CRC Press. Breslow NE, Day NE (1980). Statistical Methods in Cancer Research, Vol. I, The Analysis of Case-Control Studies. International Agency for Research on Cancer, Lyon. Breslow NE, Day NE (1987). Statistical Methods in Cancer Research, Vol. II, The Design and Analysis of Cohort Studies. International Agency for Research on Cancer, Lyon. Hosmer DW, Lemeshow S (1989). Applied Logistic Regression, John Wiley & Sons. McCullagh P, Nelder JA (1989). Generalized Linear Models, 2nd edition, Chapman and Hall.

Office Hours

地點: 423 Joint Education Hall
時間: By appointment
聯絡方式: Guan-Hua Huang, Ph.D. Office: 423 Joint Education Hall Phone: 03-513-1334 Email: ghuang@stat.nctu.edu.tw