專題研究(一)
Independent Study
學期
108-1
學分
1
學分
當期課號
A385
永久課號
A4270
開課單位
生物醫學影像暨放射科學系
授課教師
李易展、陳志成
校區
陽明
類別
選修
上課時間表
| 節 | 週三 |
|---|---|
9 17:30–18:20 | 專題研究(一) YB134 |
* 根據陽明交大上課時間表所列
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction; 偵測腫瘤組織之核醫藥物設計原理 Introduction of molecular biology and molecular cloningIntroduction |
| 第 2 週 | Partial volume effect; 放射性污染與除污操作 Practice of bacteria culture and principlePartial volume effect |
| 第 3 週 | Partial volume correction; 放射性碘標記方法與純度分析 Practice of DNA purification by spectrophotometryPartial volume correction |
| 第 4 週 | Holiday; [123I]FIAU核醫藥物之放射性同位素標記 Practice of enzyme digestion for plasmid and electrophoresisHoliday |
| 第 5 週 | BMD measurement; [123I]IBZM核醫藥物之純化與放射化學純度分析 Practice of DNA ligation and transformationBMD measurement |
| 第 6 週 | BMD calculation; Radio-TLC and HPLC:儀器原理與操作 Practice of polymerase chain reactionBMD calculation |
| 第 7 週 | TB measurement; 腫瘤細胞培養 Practice of plasmid mappingTB measurement |
| 第 8 週 | TB calculation; 18F-黑色素造影劑之放射合成與腫瘤細胞攝取 Practice of bioinformatics in genebank of PubmedTB calculation |
| 第 9 週 | Midterm Exam; 期中報告 Midterm reportMidterm Exam |
| 第 10 週 | 全校運動會 |
| 第 11 週 | PSF modeling; 18F-FAc造影劑之放射合成與腫瘤細胞攝取 Introduction of protein analysisPSF modeling |
| 第 12 週 | PSF measurement; 標靶奈米金的製備與純化 Practice of protein extraction and quantificationPSF measurement |
| 第 13 週 | Scatter correction; 標靶奈米金的I-131/In-111標記 Practice of protein denature and SDS-PAGEScatter correction |
| 第 14 週 | Nuclear imaging on the web; 實驗動物(mouse and rat)之腫瘤誘發 Practice of immunoblot analysisNuclear imaging on the web |
| 第 15 週 | PACS in nuclear medicine; 腫瘤標靶藥物(111In-C225-LipoDOX)製備與純化 Practice of buffer preparation for electrophoresisPACS in nuclear medicine |
| 第 16 週 | FBP reconstruction; 腫瘤標靶藥物(111In-C225-LipoDOX)之生物分布 Practice of densitometric analysisFBP reconstruction |
| 第 17 週 | CBP reconstruction; 荷腫瘤實驗動物之分子標靶造影 Introduction of DNA transfection and practiceCBP reconstruction |
| 第 18 週 | Final Exam; 期末報告 Final ReportFinal Exam |