免疫藥物基因體學
Immunopharmacogenomics
| 節 | 週二 |
|---|---|
9 17:30–18:20 | 免疫藥物基因體學 BI303 3 節連堂 |
A 18:30–19:20 | |
B 19:30–20:20 |
* 根據陽明交大上課時間表所列
The course content is a systematic introduction to immuno-pharmaco-genomics and how to translate pharmacogenomics research into clinical reality. We will discuss high-throughput bio-signatures screening, immunogenomics, single-cell genomics, and applications of current advanced omics technologies. Insights gained from immuno-pharmaco-genomics can contribute to the therapeutic design and therapeutic strategies of oncology, hematology, autoimmune diseases, and infectious diseases.
Analysis: Programming Language: Python, R Experience on RNA-seq and WES Fundamental knowledge: 1. Immunology 2. Human genetics 3. Single-cell genomics
attending course (20%), oral presentation (50%), exam (30%)
| 週次 | 主題 |
|---|---|
| 第 1 週 | Overview of immunopharmacogenomics in precision medicine |
| 第 2 週 | Fundamental knowledge of Immunopharmacogenomics: genetic variants in human diseases |
| 第 3 週 | Mid-term exam (1) |
| 第 4 週 | Fundamental knowledge of Immunopharmacogenomics: Human leukocyte antigen (HLA) repertoire in human disease |
| 第 5 週 | Immunopharmacogenomics in autoimmune diseases (1) |
| 第 6 週 | Immunopharmacogenomics in autoimmune diseases (2) |
| 第 7 週 | Mid-term oral presentation and discussion-(1) |
| 第 8 週 | Mid-term oral presentation and discussion-(2) |
| 第 9 週 | Mid-term exam (2) |
| 第 10 週 | Fundamental knowledge of Immunopharmacogenomics: immune repertoire and neoantigen |
| 第 11 週 | Immunopharmacogenomics in cancer immunotherapy (1): immune repertoire |
| 第 12 週 | Immunopharmacogenomics in cancer immunotherapy (2): neoantigen |
| 第 13 週 | Fundamental knowledge of Immunopharmacogenomics: single-cell genomics |
| 第 14 週 | Final oral presentation-1 |
| 第 15 週 | Final oral presentation-2 |
| 第 16 週 | Final Exam |
| 第 17 週 | Challenges and vision of immunopharmacogenomics |
| 第 18 週 | Challenges and vision of immunopharmacogenomics |
書名 Principles of Pharmacogenetics and Pharmacogenomics 編者 Russ Altman, Russ B. Altman, David Flockhart, David B. Goldstein 出版者 Cambridge University Press, 2012 ISBN 052188537X, 9780521885379 書名 Immunopharmacogenomics 編者 Yusuke Nakamura 出版者 Springer 2015 ISBN 9784431557265
- 地點
- 實驗一館101室
- 時間
- 星期二 14:00-15:00 (請先預約)
- 聯絡方式
- 59731 (e-mail: tmko@nctu.edu.tw )