質譜學

Mass Spectrometry

學期

109-2

學分

3 學分

當期課號

5457

永久課號

IAC6635

開課單位

應用化學系

授課教師

陳月枝

校區

光復

類別

選修

上課時間表

節	週一
5 13:20–14:10	質譜學 SB203 3 節連堂
6 14:20–15:10
7 15:30–16:20

* 根據陽明交大上課時間表所列

概述

This course covers the fundamentals of mass spectrometry, including ionization methods and mass analyzers. Basic principles of the interpretation of mass spectra will be briefly introduced. Applications of mass spectrometric methods in biochemical research will be discussed.

先修科目

Analytical chemistry, Instrumental Analysis

評分方式

Oral presentation: 30% Midterm exam:35% Final exam: 35%

課程大綱

History & Introduction to terminology and mass spectra
Ion Source (I) Electron ionization/ Chemical ionization
Ion Source (II) Fast atom bombardment/MALDI-MS/Electrospray ionization
Mass Analyzer (I) Quadrupole mass spectrometer/Ion trap mass spectrometer
Mass Analyzer (II) Time-of-flight mass spectrometer
Mass Analyzer (III) Fourier-transform mass spectrometer
Mass Analyzer (IV) Tandem mass spectrometer
Inlet system/LC/MS and GC/MS
Oral Presentation

教科書

1. Mass Spectrometry. Principles and Applications. E. de Hoffmann and V. Stroobant . 2nd Ed. 2001,John Wiley & Sons. 2. Introduction to Mass Spectrometry. J.T. Watson. Lippincott-Raven. 3. Time resolved mass spectrometry: from concept to applications. PL Urban, Y-C Chen, Y-S Wang, Wiley, 2016.

Office Hours

地點: Room 514, 5F, Photonics Building
時間: 10:00-11:00, Tuesday
聯絡方式: ext: 31527