高等消化道生理學

1.胃腸功能的調節,2.微生物組和早期生命,3.對腸道菌形成機制的當前了解,4.腸道菌如何影響免疫系統,5.腸道菌和腸道對上皮的免疫力,6.物理性屏障功能:上皮緊密連接,7.上皮通透性的變化,8.腸道菌和肝,9.肝臟為免疫器官,10.肝病期間宿主與腸道菌的相互作用, 11.分子微生物組分析,12.腸肝軸,13.腸腦軸等1.Regulation of gastrointestinal Functions, 2.Microbiome and early life, 3.Current understanding of the gut microbiota shaping mechanisms, 4.How the gut microbiota influences our immune system, 5.Microbiome and gut immunity the epithelium, 6.Physical barrier function: epithelial tight junction, 7.Changes in epithelial permeability, 8.Microbiota and Liver, 9.The Liver as an Immunological Organ, 10.Host–microbiome interactions during liver disease, 11.Molecular Microbiome Analysis, 12.Gut-Liver axis, 13.Gut-Brain axis etc.

本課程主要在進一步深入介紹胃腸道系統如何運作與整合。此課程涵蓋多個層面的胃腸道功能,包括腸道屏障功能, 腸道菌如何影響肝臟及腦部等器官, 再進一步延伸介紹到健康的功能以及與疾病相關的功能障礙的胃腸免疫生理及病理學。This course focuses on further in depth how the gastrointestinal system operates and integrates. This course covers multiple levels of gastrointestinal function, including intestinal barrier function, how gut microbiota affect organs such as liver and brain, and further extends to healthy functions and gastrointestinal immune physiology and pathology related to disease-related dysfunction.

(1)Menizibeya Osain Welcome, Gastrointestinal physiology, Springer, ISBN 978-3-319-910567 (eBook) (2) Dirk Haller, The gut microbiome in health and in disease, 2018, Springer, ISBN 978-3-319-90545-7 (eBook) (3) Hiromasa Ohira, The liver in systemic diseases, 2016, Springer, ISBN 978-4-431-55790-6 (eBook)