醣質生物學特論(二)
Special Topics on Glycobiology II
| 節 | 週四 |
|---|---|
7 15:30–16:20 | 醣質生物學特論(二) YB102 2 節連堂 |
8 16:30–17:20 |
* 根據陽明交大上課時間表所列
課程簡介醣結構與其功能,再深入探討GBPs的生物、生理功能與其在免疫、生理和疾病生成的關聯性。This course includes introduction of biological function of glycans, glycan binding proteins, glycoscience in immunity, and glycan in physiology and disease.
本課程涵蓋醣生物化學基礎知識介紹,醣質生物學(二)著重於glycan binding proteins (GBPs)的功能探討,將介紹R-, L-, P- C-, I-type lectins和galectins。第二部分將納入醣結構和GBPs與疾病之關聯性介紹。學生應可從中了解GBPs在細胞間交互作用與反應、基因調控以及疾病發生中扮演的角色。This course provide background to the field of glycobiology and focus on glycan binding proteins (GBPs), including R-, L-, P- C-, I-type lectins as well as galectins. In the second part, the correlation of glycan and GBPs to disease would be included. The students should get overall picture and the roles on the biological functions of GBPs in cell-cell interaction, gene regulation, cell response and disease progression.
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction of Glycobiology |
| 第 2 週 | a. Biological functions of Glycans and their application; b. Glycan binding protin |
| 第 3 週 | R-type lectins & L-type lectins |
| 第 4 週 | P-type lectins & C-type lectins |
| 第 5 週 | I-type lectins & Galectins |
| 第 6 週 | Glycoscience in immunity |
| 第 7 週 | Glycana in Physiology and Disease |
| 第 8 週 | Oral presentation |
| 第 9 週 | Oral presentation |
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| 第 12 週 | |
| 第 13 週 | |
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| 第 15 週 | |
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| 第 18 週 |
教科書: Essentials of Glycobiology 3rd edition Varki A, Cummings RD, Esko JD, et al., editors. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press