放射與疾病代謝
Radiation-induced metabolism and signaling pathways
| 節 | 週二 |
|---|---|
7 15:30–16:20 | 放射與疾病代謝 YB134 2 節連堂 |
8 16:30–17:20 |
* 根據陽明交大上課時間表所列
放射線與DNA傷害, 糖解反應, 氧化磷酸化以及多種代謝路徑Radiation and DNA damage, Radiation and Glycolysis, Radiation and OXPHOs, Radiation and Lipid Metabolism, Radiation and Amino Acid Metabolism
本課程銜接生物化學(二)與細胞生物學部分課程,讓學生了解與學習放射線造成或誘導相關新陳代謝重新編成 (ex. Glycolysis, Fatty acid biosynthesis)以及訊息傳遞路徑 (ex. HIF-1, Wnt) 在細胞與動物體造成的影響This course combines biochemistry (II) and cell biology courses to enable student to learn the metabolism reprogramming (ex. Glycolysis, Fatty acid biosynthesis) and signal transduction pathways (ex. HIF-1, Wnt) related to radiation-induced on cells and animal models.
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction |
| 第 2 週 | Radiation and DNA damage |
| 第 3 週 | Radiation and Glycolysis |
| 第 4 週 | Radiation and OXPHOs |
| 第 5 週 | Radiation and Lipid Metabolism |
| 第 6 週 | Radiation and Amino Acid Metabolism |
| 第 7 週 | 國定假日 |
| 第 8 週 | Mid-term Examination |
| 第 9 週 | Radiation and HIF-1α pathway |
| 第 10 週 | Radiosensitivy and Radioresistence |
| 第 11 週 | Radiation and Cell cytoskeleton |
| 第 12 週 | Radiation and Drugs/Inhibitors |
| 第 13 週 | student presentation |
| 第 14 週 | student presentation |
| 第 15 週 | student presentation |
| 第 16 週 | Final Examination |
| 第 17 週 | Online discussion: Radiation and Immune system |
| 第 18 週 | Online discussion: clinical application |
Campbell Biology: concepts & connections, 9th Edition. Chapter I-II. ISBN:9781292229478 Robbins Basic Pathology ver.10 ISBN:9789869684538 Radiologic science for technologists: physics, biology and protection, 9th edition. Chapter 6. ISBN:9789866538834