磁振造影及其對比劑
Magnetic Resonance Imaging and Contrast Agent
學期
110-1
學分
3
學分
當期課號
5750
永久課號
IBE5027
開課單位
分子醫學與生物工程研究所
授課教師
王雲銘
校區
博愛
類別
選修
上課時間表
| 節 | 週一 |
|---|---|
2 09:00–09:50 | 磁振造影及其對比劑 BI303 3 節連堂 |
3 10:10–11:00 | |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
概述
中文簡介 : 本課程的目的是提供物化學有關核磁共掁及醫學生物磁掁造影的基礎知識,以及磁振對比劑之設計、研發、製造、臨床實驗、市場現況及未來發。 英文簡介 : The purpose of this course if to provide physiochemical fundamentals of nuclear magnetic resonance (NMR) and biomedical magnetic resonance imagine (MRI); and the design, research and development, manufacturing, clinical studies, market analysis and future directions of MRI contrast enhancement agents.
評分方式
Paper reading Data research
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1. Introduction to In vivo and in vitro diagnostics and modalities. 2. Overview of in vivo contrast enhancement agents. |
| 第 2 週 | 中秋連假 |
| 第 3 週 | Nuclear magnetic resonance phenomenon and relaxation. |
| 第 4 週 | Nuclear magnetic resonance phenomenon and relaxation. |
| 第 5 週 | 國慶連假 |
| 第 6 週 | 1. Magnetic resonance imaging (MRI) and contrast. 2. MRI contrast enhancement agents-Classifications. |
| 第 7 週 | Some general chemistry backgrounds of lanthanide and transition metal ions and complexes. |
| 第 8 週 | 期中考 |
| 第 9 週 | MRI contrast enhancement agents-Basic scientific studies, proof of principles, drug discovery and developments, preclinical and clinical phase I, II and III studies. |
| 第 10 週 | MRI contrast enhancement agents-Safety issues. |
| 第 11 週 | MRI contrast enhancement agents-Efficacy issues. |
| 第 12 週 | MRI contrast enhancement agents-Manufacturing and clinical studies. MRI contrast enhancement agents-Market analysis |
| 第 13 週 | MRI contrast enhancement agents-Tissue and organ specificity. MR gene expression imaging and molecular imaging. |
| 第 14 週 | MRI contrast enhancement agents and nanobiotechnology. MRI contrast enhancement agents-Final presentations |
| 第 15 週 | Other topics: Patent issues, Nephrogenic Systemic Fibrosis (NSF)/Nephrogenic Fibrosing Dermopathy (NFD), Future directions, etc. |
| 第 16 週 | 期中考 |
教科書
Textbooks and research papers: Several reference books and classic, review and current research papers will be used ( to be announced )