生物統計學
Biostatistics
學期
110-1
學分
2
學分
當期課號
A345
永久課號
A1291
開課單位
物理治療暨輔助科技學系
授課教師
陳瓊梅
類別
必修
上課時間表
| 節 | 週一 |
|---|---|
3 10:10–11:00 | 生物統計學 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
教學方式
1. 了解統計的基本概念、常用的統方法與如何正確使用統計。 2. 能以正確的表達統計問題及執行統計分析並解釋分析結果
評分方式
作業 30% 課堂小考 40% 期中、末考 30%
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1. Introduction: population vs sample 2. Data characteristics 3. SPSS |
| 第 2 週 | 中秋節調整放假 |
| 第 3 週 | Descriptive statistics 1. mean, standard deviation 2. median, Q1, Q3 3. coefficient of variation 4. Using SPSS |
| 第 4 週 | Commonly used distributions: 1. Normal and Bernoulli distributions 2. Excel 3. Sampling distribution of sample mean (for continuous data) 4. Binomial distribution (for binary data) |
| 第 5 週 | 國慶日調整放假 |
| 第 6 週 | 1. Law of large number (LLN) 2. Central limit theorem |
| 第 7 週 | Point estimation for the population mean (I) 1. Point estimation and interval estimation 2. One sample inference: mean 3. t-distribution |
| 第 8 週 | Point estimation (II) Two independent samples: difference in means and proportions |
| 第 9 週 | Point estimation for the population proportion (III): 1. One sample: proportion 2. Two independent samples: difference in proportions |
| 第 10 週 | Testing (I) 1. Null hypothesis and alternative hypothesis 2. Significant level 3. P-value, Critical region and critical value |
| 第 11 週 | Testing (II): 1. Procedure of conducting testing 2. Type I error and Type error 3. One-sample t-test 4. Two-sample t-test 5. pair t-test |
| 第 12 週 | Testing (III): 1. testing vs confidence interval 2. ANOVA |
| 第 13 週 | 1. Chi-square test 2. McNemar''s test |
| 第 14 週 | Linear regression analysis for continuous outcomes 1. linear association: Pearson''s correlation vs Spearman''a rank correlation 2. Multiple regression model |
| 第 15 週 | Regression model for the binary outcomes 1. Odds ratio 2. Logistic regression model |
| 第 16 週 | Final exam |
| 第 17 週 | Survival analysis (I) |
| 第 18 週 | Survival analysis (II) |
教科書
Textbook: Biostatistics, basic concepts and methodology for the health sciences, 10th edition. Daniel and Cross, 2014, Wiley. Reference ‧ 生物統計原理 第2板 Principle of Biostatistics, 2nd ed. 原著Pagano et la., 翻譯:林維森等 歐亞書局 生物醫學統計概論,戴政與江淑瓊著