生物化學
Biochemistry
| 節 | 週一 | 週四 |
|---|---|---|
3 10:10–11:00 | 生物化學 YL402 2 節連堂 | 生物化學 YL402 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
1. 醣類結構與代謝 2. 脂質結構與代謝 3. 氨基酸結構與代謝 4. 核?酸結構與代謝 1. Carbohydrate and Carbohydrate Metabolism 2. lipid and Lipid Metabolism 3. Metabolism of Nitrogenous compounds 4. Nucleotide Metabolism
課程主旨在介紹細胞內大分子 (醣類、脂質、氨基酸、核?酸) 的結構及合成與代謝反應與其參與之酵素,除影響大分子功能,亦調控細胞生理功能。合成與代謝反應的缺失常造成許多疾病,故對疾病病理機制的基礎研究、臨床醫療發展應用有助益。This course aims to introduce structures, function and metabolisms of macromolecules (including carbohydrates, lipid, amino acids and nucleotides). It also covers enzymes involved in the catabolism and the anabolism of macromolecules. The defects in the metabolic pathways are often associated with diseases. Therefore, understanding of the metabolic pathways for macromolecules could be useful for the study of disease pathogenesis and be beneficial for development of clinical therapeutics.
四次評量 (含筆試、作業、報告), 每次佔25% 4 Written exams/reports/homework, each 25%
| 週次 | 主題 |
|---|---|
| 第 1 週 | Carbohydrates: Sugars, Saccharides, Glycans (Chap. 9) |
| 第 1 週 | Carbohydrates: Sugars, Saccharides, Glycans (Chap. 9) |
| 第 2 週 | Moon Festival |
| 第 2 週 | Chemical Logic of Metabolism (Chap. 12) |
| 第 3 週 | Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13) |
| 第 3 週 | Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13) |
| 第 4 週 | Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13) |
| 第 4 週 | Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13) |
| 第 5 週 | Double Tenth Day |
| 第 5 週 | Exam 1 (Chapters 9, 12, 13) |
| 第 6 週 | Citric Acid Cycle and Glyoxylate Cycle (Chap. 14) |
| 第 6 週 | Citric Acid Cycle and Glyoxylate Cycle (Chap. 14) |
| 第 7 週 | Citric Acid Cycle and Glyoxylate Cycle (Chap. 14) |
| 第 7 週 | Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15) |
| 第 8 週 | Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15) |
| 第 8 週 | Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15) |
| 第 9 週 | Lipids (Chap. 10) |
| 第 9 週 | Exam 2 (Chapters 14, 15) |
| 第 10 週 | Lipid Metabolism I: Fatty Acids Triacylglycerols and Lipoproteins (Chap. 17) |
| 第 10 週 | Lipid Metabolism I: Fatty Acids Triacylglycerols and Lipoproteins (Chap. 17) |
| 第 11 週 | Interorgan and Intracellular coordination of Energy Metabolism in Vertebrates (Chap. 18) |
| 第 11 週 | Interorgan and Intracellular coordination of Energy Metabolism in Vertebrates (Chap. 18) |
| 第 12 週 | Lipid Metabolism II: membrane lipids, Steroids, Isoprenoids, and Eicosanoids (Chap. 19) |
| 第 12 週 | Lipid Metabolism II: membrane lipids, Steroids, Isoprenoids, and Eicosanoids (Chap. 19) |
| 第 13 週 | Metabolism of Nitrogenous compounds I: Principles of Biosynthesis, Utilization, and Turnover (Chap.20) |
| 第 13 週 | Exam 3 (Chapters 10, 17, 18, 19) |
| 第 14 週 | Metabolism of Nitrogenous compounds I: Principles of Biosynthesis, Utilization, and Turnover (Chap.20) |
| 第 14 週 | Metabolism of Nitrogenous compounds II: Amino Acids, Porphyrins, and Neurotransmitters (Chap.21) |
| 第 15 週 | Metabolism of Nitrogenous compounds II: Amino Acids, Porphyrins, and Neurotransmitters (Chap.21) |
| 第 15 週 | Nucleotide Metabolism (Chap.22) |
| 第 16 週 | Nucleotide Metabolism (Chap.22) |
| 第 16 週 | Exam 4 (Chapters 20, 21, 22) |
| 第 17 週 | 彈性補充教學週 Mechanisms of Signal Transduction (Chap23) |
| 第 17 週 | 彈性補充教學週 Mechanisms of Signal Transduction (Chap23) |
| 第 18 週 | 彈性補充教學週 Photosynthesis (Chap. 16) |
| 第 18 週 | 彈性補充教學週 Photosynthesis (Chap. 16) |
Biochemistry (4th. ed.), Mathews, Van Holde, Appling, and Anthony-Cahill 2012