DNA損害,修復及癌化機制特論(一)
Special Topics in DNA damage,Repair and Carcinogenesis(I)
| 節 | 週一 |
|---|---|
5 13:20–14:10 | DNA損害,修復及癌化機制特論(一) YR509 2 節連堂 |
6 14:20–15:10 |
* 根據陽明交大上課時間表所列
1. DNA損傷之介紹與相關研究 2. DNA修復之介紹與相關研究 3. 癌化過程之介紹與相關研究 4. 研究DNA損傷,修復與癌化過程之實驗設計與分子工具1. Introduction and study of DNA damages 2. Introduction and study of DNA repair 3. Introduction and study of carcinogenesis 4. Experimental design and molecular tools for study of DNA damage, repair and carcinogenesis
1.瞭解DNA損傷,修復與癌化過程之發展歷程 2.瞭解DNA損傷,修復與癌化過程之原理 3.瞭解DNA損傷,修復與癌化過程之機制 4.瞭解DNA損傷,修復與癌化過程之研究方法 5.瞭解DNA損傷,修復與癌化過程之應用1. Introduction of DNA damage, repair and carcinogenesis 2. Priciple of DNA damage, repair and carcinogenesis 3. Mechanisms of DNA damage, repair and carcinogenesis 4. Experimental design for study of DNA damage, repair and carcinogenesis 5. Molecular tools for study of DNA damage, repair and carcinogenesis
1. 上台報告 2. 團體討論報告 3. 書面期末報告1. Paper presentation 2. Group discussion and presentation 3. Final report
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction 課程簡介 |
| 第 2 週 | 9/22 DNA damage I-Oxidative DNA damages |
| 第 3 週 | DNA damage II-Bulky DNA damages |
| 第 4 週 | DNA damage III- DNA strand break-1 |
| 第 5 週 | 10/12 DNA damage III- DNA strand break-2 |
| 第 6 週 | Paper discussion-DNA damage |
| 第 7 週 | DNA repair I-Base excision repair |
| 第 8 週 | DNA repair II-Nucleotide excision repair |
| 第 9 週 | DNA repair III-Recombination repair |
| 第 10 週 | Paper discussion-DNA repair I |
| 第 11 週 | Paper discussion-DNA repair II |
| 第 12 週 | Carcinogenesis I-Overview |
| 第 13 週 | Carcinogenesis II-Cell model based study |
| 第 14 週 | Carcinogenesis III-Animal model-based study |
| 第 15 週 | Paper discussion- carcinogenesis |
| 第 16 週 | Presentation-I |
| 第 17 週 | Presentation-II |
| 第 18 週 | Presentation-III |
DNA Repair and Mutagenesis (second edition, 2016, Errol C. Friedberg)