醫學物理及心臟影像定量
Medical Physics and Radionuclide Cardiac Imaging and Quantification
| 節 | 週一 |
|---|---|
3 10:10–11:00 | 醫學物理及心臟影像定量 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
This course covers a wide spectrum of hybrid nuclear cardiac imaging and quantification. The course will start with an introduction of medical physics and instrumentation of various medical imaging systems, followed by a comprehensive description of image generation, reconstruction and correction for advanced hybrid radionuclide imaging. Methodology and validation of nuclear cardiac image quantification for the detection of abnormalities of myocardial perfusion and left ventricular function will be extensively described and experimental data and clinical cases will be illustrated accordingly. In addition, special lectures for advanced molecularly targeted and sympathetic cardiac imaging and quantification will be presented. Ultimately, students will be provided with a unique Yale software package (Wackers-Liu CQ?) for nuclear cardiac SPECT and PET quantifications. This software package can be installed in students’ computers and used for teaching and research purposes. The course will be concluded with a step-by-step demonstration by the instructor as well as with hand-on practices by the students to use the Wackers-Liu CQ? software and to learn clinical diagnoses based on the images and quantitative results of several preloaded clinical cases.
After this course, students are expected to: 1. Understand the basics of nuclear medicine and the methods of hybrid radionuclide image generation, reconstruction and quantification, 2. Have comprehensive acquaintance of recent developments in hybrid SPECT/CT, PET/CT and PET/MR cardiac imaging technology, 3. Use sophisticated quantification software to process and analyze cardiac SPECT and PET images for precise clinical diagnoses based on the images and quantitative results of myocardial perfusion and sympathetic innervation studies.
Students attending and completing the course are required to submit a final written report (~ 10 pages), preferably in English, for evaluation of the knowledge and technology learned and gained from this course. The course attendees will be graded, using the grading system: A+ (>= 90), A (85 – 89), A- (80 – 84), B+ (75 – 79), B (70 – 74), B- (65 – 69) and C (< 65), based on quality of the final report and attendance record of the students.
| 週次 | 主題 |
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| 第 1 週 | |
| 第 2 週 | |
| 第 3 週 | |
| 第 4 週 | |
| 第 5 週 | |
| 第 6 週 | |
| 第 7 週 | |
| 第 8 週 | |
| 第 9 週 | Basic physics in nuclear medicine |
| 第 10 週 | Basic instrumentation principles of radiation detectors for radionuclide imaging |
| 第 11 週 | Planar, SPECT, PET, MRI, X-ray, CT imaging and instrumentation |
| 第 12 週 | Hybrid SPECT/CT, PET/CT and PET/MR imaging and instrumentation |
| 第 13 週 | Radionuclide image reconstruction and correction |
| 第 14 週 | Basic anatomy of the heart in nuclear cardiac imaging, planar radionuclide imaging and equilibrium radionuclide angiocardiography (ERNA), and quantification |
| 第 15 週 | SPECT and PET quantifications of myocardial perfusion and left ventricular function |
| 第 16 週 | Absolute quantification of myocardial focal tracer uptake from molecularly targeted cardiac imaging, and quantification of myocardial sympathetic innervation from Iodine-123-mIBG cardiac imaging |
| 第 17 週 | 彈性上課: (Course review and outline of final report) Demonstration and hand-on exercise with the Yale SPECT and PET quantification software (Wackers-Liu CQ?) for the detection of myocardial perfusion and function abnormalities |
| 第 18 週 |
1.教科書名:Physics in Nuclear Medicine 作 者:Simon R. Cherry, James A. Sorenson, and Michael E. Phelps 出 版 社:ELSEVIER, Philadelphia, PA, USA 2.教科書名:Hybrid Imaging in Cardioavascular Medicine 作 者:Yi-Hwa Liu and Albert J. Sinusas, eds. 出 版 社:CRC Press, Taylor & Francis Group, London, UK 3.教科書名:Cardiovascular Imaging 作 者:Yi-Hwa Liu and Frans J. Th. Wackers, eds. 出 版 社: CRC Press, Taylor& Francis Group, London, UK