腦科學實習
Experimental Brain Science
| 節 | 週日 |
|---|---|
N 12:20–13:10 | 腦科學實習 YL845 |
* 根據陽明交大上課時間表所列
學生選取4週完整時間,分別至4位教授實驗室進行實驗學習,各老師就該專門研究進行實驗設計教學及評分。 Students arrange their time to learn from different professors’ laboratories in a month. Each instructor for this course may teach and evaluate experimental designs in his professional field.
課程設計為使學生能於一個月的課程(暑假),到2~4位教授研究室深入瞭解專業研究計術,適時進行實驗操作,並提出相關實驗設計。教授則按各專業研究提出實驗設計之修正。The course is designed for students through rounding research laboratories for a month in order to learn professional research techniques, having adequate processing experiment and further submitting related experimental designs that were amended by instructors in different fields.
各老師就學生到各實驗室表現情況及實驗設計報告給予評分。將4位教授評分作平均。 Each instructor for this course may decide the best grading methods to evaluate the learning progress of the students by their performance and experimental design reports. Finally we will average students’ grades from the four instructors.
| 週次 | 主題 |
|---|---|
| 第 1 週 | 課程簡介 |
| 第 2 週 | |
| 第 3 週 | 腦磁圖之臨床應用及相關研究 |
| 第 4 週 | 神經內分泌學、腦影像、精神分裂症與情感症之研究 |
| 第 5 週 | 在數秒內看見你的腦在做甚麼? (observing what is going on in your brain in seconds) |
| 第 6 週 | 腦中風後的可塑與修復:從動物模型到臨床試驗 |
| 第 7 週 | 精神醫學外顯型定義方法研究 |
| 第 8 週 | 腦電磁波訊號之記錄、分析、應用及實驗設計 |
| 第 9 週 | MRI實驗設計與訊號分析 |
| 第 10 週 | 多功能生理記錄系統之軟硬體開發 |
| 第 11 週 | 睡眠及自主神經科學研究設計及實作 |
| 第 12 週 | 以分子細胞生物技術探討神經退化暨神經保護機轉 |
| 第 13 週 | 利用基因轉植鼠及細胞株研究阿茲海默症的致病機制 |
| 第 14 週 | 評估小鼠的記憶、焦慮與類似憂鬱的行為 |
| 第 15 週 | 以基因變異小鼠研究聽覺與平衡障礙 |
| 第 16 週 | 探討自律神經病變之腦循環調節異常 |
| 第 17 週 | 功能性腦造影之應用與實驗設計 |
| 第 18 週 | 期末考 |
1. Chen, C. C., Hsieh, J. C., Wu, Y. Z., Lee, P. L., Chen, S. S., Niddam, D. M., Yeh, T. C., and Wu, Y. T. (2008) Mutual-information-based approach for neural connectivity during self-paced finger lifting task. Human Brain Mapping 29:265-280 2. Lin, Y. Y., Hsiao, F. J., Shih, Y. H., Yiu, C. H., Yen, D. J., Kwan, S. Y., Wong, T. T., Wu, Z. A., and Ho, L. T. (2007) Plastic Phase-locking and Magnetic Mismatch Response to Auditory Deviants in Temporal Lobe Epilepsy. Cerebral Cortex 17:2516-2525 3. Lu, C. L., Liu, C. C., Fuh, J. L., Liu, P. Y., Wu, C. W., Chang, F. Y., and Lee, S .D. (2007) Irritable Bowel Syndrome and Negative Appendectomy: A Prospective Multivariable Investigation. GUT 56:655-660. 4. Kuo, T. B. J., Li, J. Y.?, Hsieh, S. S. Y., Chen, J. J., Tsai, C. Y., and Yang, C. C. H.* (2010) Effect of aging on treadmill exercise induced theta power in the rat. Age 32:297-308 5. Lee, P. S, Chen, Y. S., Hsieh, J. C., Su, T. P., and Chen, L. F.* (2010) Distinct neuronal oscillatory responses between patients with bipolar and unipolar disorders: a magnetoencephalographic study. Journal of Affective Disorders 123:270-275 6. Kuo, T. B. J., Shaw, F. Z., Lai, C. J., and Yang, C. C. H.* (2008) Asymmetry in sympathetic and vagal activities during sleep-wake transitions. Sleep 31:311-320 7. Wu, C. L., Chen, S. D., Yin, J. H., Hwang, C. S., and Yang, D. I* (2010) Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition. Neurobiology of Disease 40:146-154 8. Roberson, E. D., Scearce-Levie, K., Palop, J. J., Yan, F., Cheng, I. H., Wu, T., Gerstein, H., Yu, G. Q., and Mucke, L. (2007) Reducing endogenous tau ameliorates amyloid-b induced deficits in an Alzheimer’s disease mouse model. Science 316:750-754