校際選修

115-1 選課時程

進行中

  • 初選第一階段 6/15/2026
  • 初選第二階段 6/22/2026
  • 校際選修 8/24/2026
  • 初選第三階段 8/31/2026
  • 開學後加退選 9/7/2026
  • 逾期加退選 9/21/2026
選課資源

轉譯醫學

Translational Medicine

學期
110-1
學分
3 學分
當期課號
B273
永久課號
A6777
開課單位
分子醫學博士學位學程
授課教師
吳國瑞、郭英調、蔡世峯、謝世良、劉扶東、陳儀莊、陳垣崇、謝清河
類別
選修
上課時間表
週三
2
09:00–09:50
轉譯醫學
4 節連堂
3
10:10–11:00
4
11:10–12:00
N
12:20–13:10

* 根據陽明交大上課時間表所列

概述

Introduction, translational research, animal models, prodrug design & development, preclinical & clinical development, IP/VC & biotech start-up, and special lectures & student presentation of final projects.

教學方式

1. Understanding mechanisms of human diseases and relevant research models; 2. Learning the development process of new drugs or theranostics for diagnosis, prevention and treatment of human diseases; 3. Learning bioethical issues and regulatory guidelines relevant to human research.

評分方式

Class attendance & participation (50%), and final proposal (50%).

週次計畫
週次主題
第 1 週9/1 09:30-10:50 Introduction to precision, genomics, and translational medicine (Dr. 郭沛恩) 9/1 11:00-12:20 Effective scientific communications (Dr. 謝清河) 9/8 09:30-10:50 Precision management of non-small cell lung cancer (Dr.楊泮池) 9/8 11:00-12:20 MicroRNA translational research (Dr. 卓夙航) 9/15 09:30-10:50 Glycomedicine and human diseases (Dr. 謝世良) 9/15 11:00-12:20 Cancer genomics and bioinformatics (Dr. 周玉山)
第 2 週09:30-10:50 Transgenic mice and translational research (Dr. 陳佑宗) 11:00-12:20 Preclinical toxicology and safety pharmacology (Dr. 陳筱苓)
第 3 週09:30-10:50 Modeling prostate cancer metastasis to identify novel treatment by the phenotypic screen (Dr. 蕭培文) 11:00-12:20 Tumor immunology and immunotherapy (Dr. 林國儀)
第 4 週09:30-10:50 Development of biologics (Dr. 阮大同) 11:00-12:20 Translation of small and large molecules: the difference and similarity (Dr. 顧曼芹)
第 5 週09:30-10:50 From Bench to Candidate: Lead identification and lead optimization (Dr. 謝興邦) 11:00-12:20 PK/PD/PG Based Drug Development and Examples in Taiwan (Dr. 胡幼圃)
第 6 週09:30-10:50 Antibody engineering and prodrug development (Dr. 羅傅倫) 11:00-12:20 Nanobiotechnology and vaccine development (Dr. 胡哲銘)
第 7 週09:30-10:50 Regulatory approval for clinical trials (Dr. 高純琇) 11:00-12:20 VC and financial management in biotech industry (Dr. 李世仁)
第 8 週09:30-10:50 Biotech in Taiwan (Dr. 張立言) 11:00-12:20 IRB and conflict of interests (Dr. 戴正德)
第 9 週09:30-10:50 IP protection and patent application (Dr. 許瑞城) 11:00-12:20 Clinical research design, monitoring and data collection (Dr. 林家齊)
第 10 週09:30-10:50 Huntington''s disease: clinical trials and drug development (Dr. 陳儀莊) 11:00-12:20 Genome instability in translational cancer biology (Dr. 張智芬)
第 11 週09:30-10:50 NGS applications and precision medicine (Dr. 蔡世?) 11:00-12:20 Antibody engineering and targeted therapy (Dr. 吳漢忠)
第 12 週09:30-10:50 Dengue & Translational Medicine (Dr. 林宜玲) 11:00-12:20 Epigenetics in development and disease (Dr. 阮麗蓉)
第 13 週09:30-10:50 Nutrition epidemiology to understand the relationship between diet, nutrition, and diseases (Dr. 潘文涵) 11:00-12:20 Advances of migraine (Dr. 王署君)
第 14 週09:30-12:20 Student presentation (I) (Dr. 謝清河)
第 15 週09:30-12:20 Student presentation (II) (Dr. 謝清河)
第 16 週
第 17 週
第 18 週
教科書

1. Horig H et al. “Obstacles and opportunities in translational research”. Nat. Med, 2005;11:705. 2. Zerhouni EA. “Translational and clinical science--Time for a new vision”. NEJM. 2005;353:1621. 3. Cressey D. “Talking up translation”. Nature. 2010;463:422. 4. Class handouts.