生物統計學
Biostatistics
學期
110-2
學分
3
學分
當期課號
C688
永久課號
A1292
開課單位
生物醫學工程學系
授課教師
陳瓊梅
校區
陽明
類別
必修
上課時間表
| 節 | 週五 |
|---|---|
5 13:20–14:10 | 生物統計學 YX503 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
教學方式
1. 了解統計的基本概念、常用的統方法與如何正確使用統計。 2. 能以正確的表達統計問題及執行統計分析並解釋分析結果 1. Understand the basic concepts and know how to use appropriate methods to analyze data 2. Know how to conduct the analysis and interpret the analysis results
評分方式
作業 30% 課堂小考 40% 期中、末考 30%
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1. Introduction: population vs sample 2. Data characteristics and coding 3. SPSS |
| 第 2 週 | Descriptive statistics 1. mean, standard deviation 2. median, Q1, Q3 3. coefficient of variation 4. Using SPSS |
| 第 3 週 | Commonly used distributions: 1. Normal and Bernoulli distributions 2. Excel 3. Sampling distribution of sample mean (for continuous data) Binomial distribution (for binary data) |
| 第 4 週 | 1. Law of large number (LLN) 2. Central limit theorem |
| 第 5 週 | Point estimation for the population mean (I) 1. Point estimation and interval estimation 2. One sample inference: mean 3. t-distribution |
| 第 6 週 | Point estimation (II) Two independent samples: difference in means and proportions |
| 第 7 週 | Point estimation for the population proportion (III): 1. One sample: proportion 2. Two independent samples: difference in proportions |
| 第 8 週 | Testing (I) 1. Null hypothesis and alternative hypothesis 2. Significant level P-value, Critical region and critical value |
| 第 9 週 | Testing (II): 1. Procedure of conducting testing 2. Type I error and Type error 3. One-sample t-test 4. Two-sample t-test 5. pair t-test |
| 第 10 週 | Testing (III): 1. testing vs confidence interval 2. ANOVA |
| 第 11 週 | Mid-term exam |
| 第 12 週 | 1. Chi-square test 2. McNemar''s test 3. ROC curve |
| 第 13 週 | Linear regression analysis for continuous outcomes 1. linear association: Pearson''s correlation vs Spearman''a rank correlation 2. Multiple regression model-(1) |
| 第 14 週 | 1. Multiple regression model-(2) 2. R-square 3. Dummy variables and the interpretation |
| 第 15 週 | Regression model for the binary outcomes 1. Confounding variables 2. Odds ratio 3. Logistic regression model |
| 第 16 週 | Dragon Boat Festival |
| 第 17 週 | Survival analysis (I) |
| 第 18 週 | Survival analysis (II) |
教科書
Textbook: Biostatistics, basic concepts and methodology for the health sciences, 10th edition. Daniel and Cross, 2014, Wiley. Reference ‧ 生物統計原理 第2板 Principle of Biostatistics, 2nd ed. 原著Pagano et la., 翻譯:林維森等 歐亞書局 生物醫學統計概論,戴政與江淑瓊著