生物統計學
Biostatistics
學期
111-1
學分
2
學分
當期課號
111408
永久課號
BEPT10034
開課單位
公共衛生學科
授課教師
陳瓊梅
校區
陽明
類別
必修
上課時間表
| 節 | 週一 |
|---|---|
3 10:10–11:00 | 生物統計學 YB624 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
概述
1. Understand the basic concepts and know how to use appropriate methods to analyze data 2. Know how to conduct the analysis and interpret the analysis results
評分方式
HW 40% Quiz 30% Mid-term exam and Final exam 30%
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1. Introduction: population vs sample 2. Data characteristics |
| 第 2 週 | Descriptive statistics 1. mean, standard deviation 2. median, Q1, Q3 3. coefficient of variation 4 statistical software: SPSS |
| 第 3 週 | Commonly used distributions: 1. Normal distribution 2. Binomial distribution (for binary data) 2. Excel 3. Sampling distribution of sample mean 4. LLN, CLT |
| 第 4 週 | Point estimation for the population mean (I): 1. Point estimation and interval estimation 2. One sample inference: mean 3. t-distribution |
| 第 5 週 | 國慶日調整放假 |
| 第 6 週 | Point estimation (II): Two independent samples: difference in means and proportions |
| 第 7 週 | Point estimation for the population proportion (III): 1. One sample: proportion 2. Two independent samples: difference in proportions |
| 第 8 週 | Mid-term exam |
| 第 9 週 | Testing (I): 1. Null hypothesis and alternative hypothesis 2. Type I error and Type 2 error |
| 第 10 週 | Testing (II): 3. Significant level 4. P-value, Critical region and critical value 5. Type I error and Type II error 4. One-sample t-test: one-tail t test and two-tail t test |
| 第 11 週 | Testing (III): 1. Two-sample t-test 2. Test vs confidence interval |
| 第 12 週 | 1. pair t-test 2. two-sample proportions test |
| 第 13 週 | Chi-square test ANOVA McNemar's test |
| 第 14 週 | Linear regression analysis for continuous outcomes 1. linear association: Pearson''s correlation vs Spearman''a rank correlation 2. Multiple regression model |
| 第 15 週 | Logistic regression model for binary outcomes 1. Odds ratio 2. Logistic regression model |
| 第 16 週 | Final exam |
| 第 17 週 | 開國紀念日調整放假 |
| 第 18 週 | Survival analysis |
教科書
Textbook: Biostatistics, basic concepts and methodology for the health sciences, 10th edition. Daniel and Cross, 2014, Wiley. Reference ‧ 生物統計原理 第2板 Principle of Biostatistics, 2nd ed. 原著Pagano et la., 翻譯:林維森等 歐亞書局 生物醫學統計概論,戴政與江淑瓊著