應用疫苗學初探-從產業研發、疫苗政策、到全球衛生
An introduction to applied vaccinology- from vaccine development, vaccine policy, to global health
| 節 | 週五 |
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5 13:20–14:10 | 應用疫苗學初探-從產業研發、疫苗政策、到全球衛生 YS405 2 節連堂 |
6 14:20–15:10 |
* 根據陽明交大上課時間表所列
疫苗學是新冠肺炎全球大流行下,被注目並快速發展的領域。本課程旨在領學生入門,一窺疫苗研發的歷史及當前發展、了解產業的角度、或從政府的角度了解公費疫苗的決策過程,並探討其在全球衛生實務的衍生議題。 Applied vaccinology is a fast-growing field under the SARS-CoV-2 pandemic. This course aims to introduce 1) the history and development of vaccines 2) the vaccines industry 3) policy decision-making on public vaccination 4) vaccines implication in global health. 本課程屬1學分初階課程,透過講課與討論的方式進行。 課程內容 一,介紹疫苗學的基本要素和概念。 二,介紹疫苗的歷史與最新的發展。 三,從疫苗產業的角度來了解疫苗。 四,疫苗研發之臨床前試驗、人體試驗、及法規登記 五,從公共衛生、全球衛生治理的角度來談疫苗。 六,探討公費疫苗政策的制定過程及其議題。 七,概論疫苗發展的挑戰,以及未來的展望。 預期成果 學生對疫苗相關領域有比較全面的認識,並啟發學生運用此基礎,或投身於疫苗相關的研究。 This is a 1-credit course, delivered through lectures and in-class discussions. The course will cover the following topics: 1. Introduction to applied vaccinology: basic elements and concepts 2. From the history of vaccination to recent advances in vaccine development 3. Vaccine industry and good manufacturing practices (onsite visit to Medigen Vaccine Company – Hsinchu) 4. Vaccine development: from preclinical, clinical, to regulatory approval 5. The implication of vaccine on public health and global health 6. Public vaccine policy decision-making, frameworks and issues 7. Advanced topics
專業知識與自主學習: 主動學習能力, 終身學習能力 溝通協調與團隊合作:人際關系與溝通技巧 邏輯思辨和自我反省: 具備邏輯推理能力, 基於實證提出最佳決策, 從工作中學習及成長
期末作業 40% 期末報告 30% 課堂參與討論 30% Final assignment 40% Final presentation 30% In-class discussion 30%
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| 第 10 週 | 1. Introduction/From the history of vaccination to recent advances in vaccine development |
| 第 11 週 | 2. An introduction to immunology (Dr. Mei Yun Lin林美雲博士) |
| 第 12 週 | 3. Global actors in COVID-19 response and attitudes towards vaccination |
| 第 13 週 | 4. A tour to vaccine manufacturing site (visit to Hsinchu) |
| 第 14 週 | 5. Estimating vaccine effectiveness and safety: general methodological principles |
| 第 15 週 | 6. Understanding public vaccine policymaking |
| 第 16 週 | 7. National immunization programs and infectious disease control (Dr. Ding-Ping Liu劉定萍教授) |
| 第 17 週 | 8. Student Presentations |
| 第 18 週 | 補充教學週 |
1. Plotkin, S. A., Orenstein, W., Offit, P. A., & Edwards, K. M. (2017). Vaccines E-Book. Elsevier Health Sciences. 2. Kimberlin, D. W., Brady, M. T., & Jackson, M. A. (2018). Red Book (2018): Report of the Committee on Infectious Diseases. American academy of pediatrics. 3. Plotkin, S. A. (Ed.). (2011). History of vaccine development. Springer Science & Business Media. Extended readings: 1. Gilbert, S., & Green, C. (2021). Vaxxers: The Inside Story of the Oxford AstraZeneca Vaccine and the Race Against the Virus. Hodder & Stoughton. 2. Loder, N. (2021). The First Shots: The Epic Rivalries and Heroic Science Behind the Race to the Coronavirus Vaccine. Nature, 28-29. 3. Kingdon, J. W., & Stano, E. (1984). Agendas, alternatives, and public policies (Vol. 45, pp. 165-169). Boston: Little, Brown.