功能性磁振造影分析
fMRI data analysis
| 節 | 週三 |
|---|---|
3 10:10–11:00 | 功能性磁振造影分析 YL824 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
Functional magnetic resonance imaging (fMRI) is the major tool to understand the workings of the human mind. It records changes in blood oxygenation level that indirectly reflect neural activity. Through analyzing how these signals change as a result of cognitive activity, neuroscientists are beginning to understand the neurobiological foundations of cognition, emotion, motivation, memory, language, learning, and decision making. This course will introduce major data analysis methods, their theories and applications. Students will analyze different datasets using these methods. 功能性磁振造影是研究人類心智運作的主要工具,它紀錄了大腦血氧濃度變化的訊號。透過分析這些因心智運作產生之生理訊號,神經科學家得以了解認知、情緒、動機、記憶、語言和學習等不同功能的神經基礎。本課程在介紹不同的訊號分析方式,其背後理論,並透過實作讓修課學生具備分析資料的基本能力。
Lab exercise: 80% In-class participation: 20%
| 週次 | 主題 |
|---|---|
| 第 1 週 | The origin of functional magnetic resonance imaging |
| 第 2 週 | Where do fMRI signals come from? MRI physics and signal generation. Chapter 3,4 (Huettel) |
| 第 3 週 | Blood-oxygen-level-dependent signals: origins and properties. Chapter 6,7 (Huettel) Lab 1 |
| 第 4 週 | Experimental design 1 Chapter 9 (Huettel) |
| 第 5 週 | Experimental design 2 |
| 第 6 週 | Data preprocessing 1 Chapter 8 (Huettel) Lab 2 |
| 第 7 週 | Data preprocessing 2 |
| 第 8 週 | General Linear Modeling: first-level analysis Chapter 10 (Huettel) Lab 3 |
| 第 9 週 | General Linear Modeling: higher-level analysis |
| 第 10 週 | General Linear Modeling: multiple comparison problem and ways to correct for it |
| 第 11 週 | General Linear Modeling: interpreting the results |
| 第 12 週 | Multivoxel pattern analysis: binary classification Chapter 11 (Huettel) Lab 4 |
| 第 13 週 | Multivoxel pattern analysis: regression approach |
| 第 14 週 | Multivoxel pattern analysis: representational similarity analysis Lab 5 |
| 第 15 週 | Multivoxel pattern analysis: representational similarity analysis |
| 第 16 週 | Next generation fMRI |
| 第 17 週 | |
| 第 18 週 |
Huettel SA, Wong AW, McCarthy G. Functional magnetic resonance imaging. Third edition. Poldrack RA, Mumform JA, Nichols TE. Handbook of functional MRI data analysis.