單細胞基因體學
Single-cell Genomics
學期
111-2
學分
3
學分
當期課號
410060
永久課號
BTBT30022
開課單位
生物科技學系
授課教師
柯泰名
校區
博愛
類別
選修
上課時間表
| 節 | 週二 |
|---|---|
2 09:00–09:50 | 單細胞基因體學 BI311 3 節連堂 |
3 10:10–11:00 | |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
概述
Single-cell genomics is rapidly becoming a revolutionary technology that is changing many areas of biological research. Through its many applications (single-cell genome sequencing, single-cell transcriptomics, and various single-cell epigenetic analysis methods), researchers can characterize the genetic and functional properties of individual cells under their natural conditions, leading to many experiments and clinical opportunities.
先修科目
molecular biology / NGS data analysis R / Python (optional)
教學方式
This is a hybrid course.
評分方式
Midterm exam, Midterm oral presentation, Final exam, Final oral presentation
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction |
| 第 2 週 | Basic genomics tools and concept |
| 第 3 週 | Single-cell transcriptomics (RNA) |
| 第 4 週 | Single-cell multi-omics (1) |
| 第 5 週 | Single-cell multi-omics (2) |
| 第 6 週 | Spatial transcriptomics |
| 第 7 週 | Single-cell data analysis (typical analysis, cell-cell interaction, RNA velocity) |
| 第 8 週 | Holiday |
| 第 9 週 | Mid-term oral presentation |
| 第 10 週 | Mid-term oral presentation |
| 第 11 週 | Standard single-cell data analysis (Seurat package) |
| 第 12 週 | Applications: single-cell genomics in cancer biology |
| 第 13 週 | Applications: single-cell genomics in neurology |
| 第 14 週 | Applications: single-cell genomics in infectious diseases |
| 第 15 週 | Final oral presentation |
| 第 16 週 | Final oral presentation |
| 第 17 週 | |
| 第 18 週 |
Office Hours
- 地點
- NYCU BioICT Building Room 628
- 時間
- Friday 16:30-17:00
- 聯絡方式
- tmko@nycu.edu.tw