鑑識分子遺傳學
Forensic Molecular Genetics
| 節 | 週一 |
|---|---|
3 10:10–11:00 | 鑑識分子遺傳學 YK104 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
The word “forensic” does not mean death and this means that molecular genetics does not just interact with murder, rape and crime in general like in CSI. “Forensic” means “pertaining to the law or the legal system”. So forensic molecular genetics is where one uses molecular genetics to answer legal questions. This may involve criminal cases like murder, rape and robbery, but in fact the most common use of forensic molecular genetics is the determination of paternity in civil cases. This course is aimed, firstly, at introducing the subject of forensic molecular genetics to those who are interested and secondly, at showing that molecular genetics is not just laboratory work and biotechnology companies. In these lectures, we will first examine how legal systems work. Most legal expertise has been gained in the UK, USA and similar legal systems, but as you will see, the basis of expert scientific testimony covers most legal systems including the codified system used in Taiwan. Then we will examine to look various aspects of DNA profiling using scientific papers with the aim of introducing you to the various methods and their applications as used in court. We will progress onto some new applications and some specific cases. This will put the methods and applications into context. This is then expanded to include things like bioterrorism. Please note that many of the papers we will be looking at do not require a great deal of knowledge of molecular genetics and are easy to understand. If you need to contact me please use ralph_kirby@icloud.com Although this is not a recommended textbook for this course and one is not needed, if you want a book on this subject I would suggest this one: "Forensic DNA Evidence Interpretation" edited by Buckleton, Triggs and Walsh. Available from Amazon. Objectives To introduce the participants to the uses made of molecular biology and genetics in a legal context.
One assignment make up the assessment for this course. I do not require long essays to be written in English and I will not be marking the assignments based on your English proficiency. The questions are based on logic, reasoning and the knowledge imparted by the course. If I can understand your answer to be correct, you will get the marks. Please submit your assignment using E3 (the new e-campus) or if there is a problem email me at ralph_kirby@icloud.com.
Outline Introduction to DNA profiling methods and their limitations Examination of real case studies DNA profiling and ethics Ancient DNA DNA evidence in court Limitations of molecular genetic evidence Biowarfare and molecular biology Assessment One assignment will be marked during the course and this will be used to produce the final course mark. Failure to hand in this assignment will result in a fail mark.
| 週次 | 主題 |
|---|---|
| 第 1 週 | Lecture 1. Introduction to the Law and Scientific Evidence. Why use Molecular Genetics. |
| 第 2 週 | Lecture 2. Where do we find Molecular Genetics in Courts of Law. |
| 第 3 週 | Lecture 3. Molecular Genetics and DNA Profiling - The Systems. |
| 第 4 週 | Lecture 4. Molecular Genetics and DNA Profiling – Populations. Start Assignment |
| 第 5 週 | Lecture 5. Real Cases and Parentage Testing. |
| 第 6 週 | Lecture 6. Low Level DNA Samples |
| 第 7 週 | Mid-Term Exam. No Lecture |
| 第 8 週 | Lecture 7. Mitochondrial DNA and Ancient DNA |
| 第 9 週 | Lecture 8. Mass Accident and Graves + DNA Intelligence Databases |
| 第 10 週 | Lecture 9. Microbial and Consumer Forensics. Biowarfare and Molecular Genetics. |
| 第 11 週 | Lecture 10. Hand in Assignment. Conservation and Molecular Genetics. Can the system be beaten.Review of Class Assignment |
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| 第 13 週 | |
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| 第 16 週 |
- 聯絡方式
- ralph_kirby@icloud.com