幹細胞生物學

本課程介紹各式幹細胞的研究與應用,包括胚胎幹細胞及體幹細胞例如造血、間葉、生 殖、神經、表皮、心臟、視覺、聽覺、肝臟、肺臟及胰臟等組織幹細胞,同時本課程也 將說明什麼是腫瘤幹細胞。本課程將透過基礎觀念的建立與了解,循序漸進介紹細胞生 長調節、幹細胞研究方法、幹細胞分化的調控機制;也會介紹 Phage display、CRISPR 等技術如何應用在幹細胞研究。同時配合指定文獻的閱讀與報告中,以建立學生對幹細 胞研究思考判斷的能力。 The Stem Cell Biology Course is primarily consisted of a series of lectures which covers from basics of the general biology of stem cells to a more in-depth discussion on various stem cell types: embryonic stem cells, adult somatic stem cells and cancer stem cells, and finally to some of their potential clinical application/implication. The course will also introduce how phage display technique and CRISPR tools can be used in stem cell research. For evaluation, students are required to write a review essay on designated research topics so that they can horn their skills in the search, organization and critical assessment of literatures.

授課方式:講授,指定文獻閱讀

成績評量: (i) A written essay on a selected topics 40 % (ii) A short presentation on a selected topics (10 min) 40 % (ii) Attendance 20 %