生物統計學
Biostatistics
學期
112-2
學分
3
學分
當期課號
113504
永久課號
MDDH10008
開課單位
公共衛生學科
授課教師
陳瓊梅
校區
陽明
類別
必修
上課時間表
| 節 | 週五 |
|---|---|
5 13:20–14:10 | 生物統計學 YX503 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
概述
1. Understand the basic concepts and know how the data structure and assumptions. 2. know how to use appropriate methods to analyze data. 3. Know how to conduct the analysis and interpret the analysis results.
評分方式
HW 30% Quiz 30% Final exam 40%
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1. Introduction: population vs sample 2. Data characteristics |
| 第 2 週 | Descriptive statistics 1. mean, standard deviation2. median, Q1, Q33. coefficient of variation4 statistical software: SPSS |
| 第 3 週 | Commonly used distributions:1. Normal distribution2. Binomial distribution (for binary data)2. Excel3. Sampling distribution of sample mean4. LLN, CLT |
| 第 4 週 | Point estimation for the population mean (I):1. Point estimation and interval estimation2. One sample inference: mean3. t-distribution |
| 第 5 週 | Point estimation (II):Two independent samples: difference in means and proportions |
| 第 6 週 | Point estimation for the population proportion (III):1. One sample: proportion2. Two independent samples: difference in proportions |
| 第 7 週 | Testing (I): 1. Null hypothesis and alternative hypothesis2. Type I error and Type 2 error |
| 第 8 週 | Testing (II):# quiz3. Significant level4. P-value, Critical region and critical value5. Type I error and Type II error4. One-sample t-test: one-tail t test and two-tail t test |
| 第 9 週 | Testing (III):1. Two-sample t-test2. Test vs confidence interval |
| 第 10 週 | 1. pair t-test2. two-sample proportions test |
| 第 11 週 | Chi-square testANOVAMcNemar's test |
| 第 12 週 | # quizLinear regression analysis for continuous outcomes1. linear association: Pearson''s correlation vs Spearman''a rank correlation2. Multiple regression model |
| 第 13 週 | Logistic regression model for binary outcomes1. Odds ratio2. Logistic regression model |
| 第 14 週 | Review |
| 第 15 週 | Survival analysis |
| 第 16 週 | Final exam |
| 第 17 週 | 自主學習 |
| 第 18 週 | 自主學習 |
教科書
Textbook: Daniel and Cross, 2019. Biostatistics: A Foundation for Analysis in the Health Science. Wiley. Reference 1. 生物統計原理 第2板 Principle of Biostatistics, 2nd ed. 原著Pagano et la., 翻譯:林維森等 歐亞書局 2. 生物醫學統計概論,戴政與江淑瓊著