基因編輯技術於疾病治療的新策略
The therapeutic strategies of gene editing techniques
學期
112-2
學分
2
學分
當期課號
131911
永久課號
PSBP30034
開課單位
生物藥學研究所
授課教師
何國牟
校區
陽明
類別
選修
上課時間表
| 節 | 週一 |
|---|---|
7 15:30–16:20 | 基因編輯技術於疾病治療的新策略 YC101 2 節連堂 |
8 16:30–17:20 |
* 根據陽明交大上課時間表所列
概述
At present, human clinical trials using CRISPR-Cas gene editing technology have just begun, although the long-term impact of the edited gene on the human body is still unknown. Compared with traditional gene editing technology, CRISPR-Cas is easier to operate, has low species restriction, and can be widely used. It is applied to general molecular biology laboratories and can perform multiple gene editing at the same time. It has completely changed and accelerated the biological research methods of the world, and provided a new method for the treatment of human diseases in the future.
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 02/19 Overview of molecular genetic technique 2 Dr. Guor Mour Her |
| 第 2 週 | 02/26 Induction of CRISPR-Cas9 2 Dr. Guor Mour Her |
| 第 3 週 | 03/04 The applications of CRISPR-Cas9 2 Dr. Guor Mour Her |
| 第 4 週 | 03/11 CRISPR-Cas9 for medical genetic screens 2 Dr. Guor Mour Her |
| 第 5 週 | 03/18 CRISPR-Cas9 for metabolic diseases 2 Dr.Guor Mour Her |
| 第 6 週 | 03/25 CRISPR-Cas9 for obesity diseases 2 Dr. Guor Mour Her |
| 第 7 週 | 04/01 CRISPR-Cas9-A tool for immunological research 2 Dr. Guor Mour Her |
| 第 8 週 | 04/08 CRISPR/Cas9 for cancer research and therapy 2 Dr. Guor Mour Her |
| 第 9 週 | 04/15 Mid-term-report (1) 2 Dr. Guor Mour Her |
| 第 10 週 | 04/22 An APOBEC3A-Cas9 base editor 2 Dr. Guor Mour Her |
| 第 11 週 | 04/29 human APOBEC 3A-Cas9 fusion 2 Dr. Guor Mour Her |
| 第 12 週 | 05/06 Transgenic Expression of Cas9 and sgRNAs 2 Dr. Guor Mour Her |
| 第 13 週 | 05/13 Zebrafish Genome Engineering Using the CRISPR–Cas9 2 Dr. Guor Mour Her |
| 第 14 週 | 05/20 RNA technology or therapeutic targets 2 Dr. Guor Mour Her |
| 第 15 週 | 05/27 High-throughput drug screening platform 2 Dr. Guor Mour Her |
| 第 16 週 | 06/03 Final-term-report (1) 2 Dr. Guor Mour Her |