微流體系統工程
Microfluidic Systems Engineering
| 節 | 週二 |
|---|---|
2 09:00–09:50 | 微流體系統工程 BI309 3 節連堂 |
3 10:10–11:00 | |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
微流體系統為可操控微量液體的整合式系統,涵蓋多種原理與工程技術。在生物醫學領域中,微流體系統可透過微量液體的操控技術與生物感測技術的整合,將必要的生物化學反應步驟微縮至一個小型的晶片上,從而達到降低樣本與試劑消耗、提升檢測速度與自動化操作的目的。這使得生物化學分析更趨向於更經濟、迅速和低門檻的方向發展。此類的微流體系統又稱為生醫晶片(Bio-chip)或實驗室晶片(Lab-on-a-chip)。 Microfluidic systems are integrated platforms designed to manipulate small liquid volumes, which include diverse principles and engineering methods. In biomedicine, these systems combine precision liquid control with biosensing techniques, to condense crucial biochemical reactions onto compact chips. This approach facilitates the reduction of sample and reagent consumption, while also accelerating detection and enabling automated procedures. Such a transition fosters biochemical analyses that are more economical, rapid, and user-friendly. These types of microfluidic systems are often referred to as “Biochip” or “Lab-on-a-chip”. 本課程旨在介紹微流體系統之基礎及其最新的研究進展。除了課堂授課外,還包含實作課程。 This course is designed to introduce the fundamentals of microfluidic systems, as well as the latest research advancements. In addition to classroom lectures, it includes lab sessions and practicum. 課程內容主要包含: 1. 微流體系統之微製程技術 (Micromanufacturing of Microfluidic Systems) 2. 流道式微流體技術:現象、元件與生醫應用 (Channel-based Microfluidics) 3. 數位微流體技術:現象、元件與生醫應用 (Digital Microfluidics) 4. 生醫晶片實作 (Micromanufacturing Demonstration and Biochip Practicum) 課程目標: 1. 瞭解生醫晶片與微流體系統的基本概念和原理 2. 掌握生醫晶片與微流體系統的微製程技術 3. 理解流道式微流體技術和數位微流體技術的應用範疇 4. 學習開發生醫晶片與微流體系統的能力 5. 探索微流體系統在生物醫學領域中的最新研究進展 核心能力訓練 1. 培養創新思考、自我學習與表達能力。 2. 培養良好的產業觀與國際觀。 3. 培養協調跨領域人才與技術整合之能力。
* 基本數學、物理概念 * Basic concepts of mathematics and physics. * 先修過生醫微機電系統與實作較佳 * It is recommended to have prior experience with BioMEMS Engineering and Experiment * 本課程含有實作課程,須先自行完成環安課程。 * The course includes lab sessions, and students must complete the environmental and safety training in advance.
以老師課堂講授為主。助教協助作業與考試評分、微流體晶片實作與學生輔導。
出席10%、作業10%、實驗報告20%、期中考20%、期末考20%、期末報告20% Attendance 10%, Assignments 10%, Laboratory Reports 20%, Midterm Exam 20%, Final Exam 20%, Final Project Presentation 20%
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction |
| 第 2 週 | Micromanufacturing: Semiconductor Manufacturing |
| 第 3 週 | No Class (中秋節 Mid-Autumn Festival) |
| 第 4 週 | Micromanufacturing: Microchannel, Polymer & Glass |
| 第 5 週 | Channel-based Microfluidics: Laminar Flow & Mixing |
| 第 6 週 | Channel-based Microfluidics: Micro Pump & Valve |
| 第 7 週 | Digital Microfluidics: Surface Tension |
| 第 8 週 | Digital Microfluidic Systems |
| 第 9 週 | Midterm Exam |
| 第 10 週 | Lab Sessions: Pre-Lab Orientation |
| 第 11 週 | Lab Sessions: Lab Tour/ Instrument Practicum |
| 第 12 週 | Lab Sessions: Fabrication of Microfluidic Chip I |
| 第 13 週 | Lab Sessions: Fabrication of Microfluidic Chip II |
| 第 14 週 | Lab Sessions: Microfluidic Manipulation and Testing |
| 第 15 週 | Final Exam |
| 第 16 週 | Final Project Presentation |
以老師課程講義為主。課程講義將彙整多本參考書目與最新研究進展。
- 地點
- BI615
- 時間
- 每堂課後與老師討論,或由 Email 與老師安排晤談時間。
- 聯絡方式
- mslee@nycu.edu.tw