生物藥劑學
Biopharmaceutics
學期
113-2
學分
3
學分
當期課號
132006
永久課號
PSPM30013
開課單位
藥學系
授課教師
胡德民、徐立峰
校區
陽明
類別
選修
上課時間表
| 節 | 週一 |
|---|---|
2 09:00–09:50 | 生物藥劑學 YK533 3 節連堂 |
3 10:10–11:00 | |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 1. Introduction to biopharmaceutics and pharmacokinetics 2. Mathematic fundamentals in pharmacokinetics |
| 第 2 週 | One-compartment model |
| 第 3 週 | Multicompartment models |
| 第 4 週 | Intravenous infusion |
| 第 5 週 | Pharmacokinetics of oral absorption |
| 第 6 週 | 1. Midterm I (1h) 2. Multiple-dosage regimens (2h) |
| 第 7 週 | Physiologic drug distribution and protein binding |
| 第 8 週 | Drug elimination and hepatic clearance |
| 第 9 週 | 1. Pharmacogenetics & drug metabolism 2. Physiologic factors related to drug absorption |
| 第 10 週 | Biopharmaceutical considerations in drug product design and in vitro drug product performance |
| 第 11 週 | Bioavailability and Bioequivalence |
| 第 12 週 | 1. Midterm 2 (1h) 2. Drug elimination, clearance, and renal clearance (2h) |
| 第 13 週 | 1. Nonlinear Pharmacokinetics 2. PK-PD relationship |
| 第 14 週 | 1. Application of pharmacokinetics to clinical situation 2. Dose adjustment in renal and hepatic disease |
| 第 15 週 | Review |
| 第 16 週 | Final exam (comprehensive) |
教科書
Applied Biopharmaceutics and Pharmacokinetics. 8th ed. Shargel, L. and Andrew, Yu B.C.