模式生物與腦科學
Model Organisms in Neuroscience
| 節 | 週三 |
|---|---|
5 13:20–14:10 | 模式生物與腦科學 YL837 2 節連堂 |
6 14:20–15:10 |
* 根據陽明交大上課時間表所列
We will first introduce different model organisms, discuss their advantages and disadvantages in using them to study neuroscience. Next, we will discuss how these animal models were used for research in neuroscience and the research advances that have been accomplished using these models. Finally, we will discuss future frontier questions in neuroscience that remain to be pursued and how these model organisms will help to address these questions. A list of model organisms includes: Mosquitos Caenorhabditis elegans Drosophila melanogaster Zebrafish Danio rerio Mus musculus Primate macaque Pig Human homo sapiens
針對大三與大四學生以及研究生安排課程,讓學生了解腦科學中不同模式生物的運用與貢獻。課程內容包含:(I)介紹不同模式生物的優缺點,包括蚊子、線蟲、果蠅、斑馬魚、小鼠、獼猴以及人等動物模型;(II)介紹運用不同模式生物進行的腦科學研究,討論這些前沿研究對腦科學領域做出的貢獻;(III)邀請運用這些模式生物進行研究的專家來演講,讓學生深入理解這些模式生物的不同與互補性質,以及主導腦科學研究發展的過程。
1. Attendance and active participation (60%) 2. Midterm: a one-page English summary on the model organisms covered so far. Pick one among the ones covered (15%) 3. Final: a final term paper (3-5 pages in English) describing a scientific question you want to address using one of the model organisms (25%)
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction |
| 第 2 週 | Drosophila melanogaster (神研所何淑君老師) |
| 第 3 週 | Drosophila melanogaster (中研院孫以瀚老師) |
| 第 4 週 | Mosquitos as a model organism (國衛院陳俊宏老師) |
| 第 5 週 | Caenorhabditis elegans (台大潘俊良老師) |
| 第 6 週 | Caenorhabditis elegans(台大潘俊良老師) |
| 第 7 週 | Holiday |
| 第 8 週 | Midterm |
| 第 9 週 | Zebrafish Danio rerio (中研院黃國華老師) |
| 第 10 週 | Mus musculus (中研院周申如老師) |
| 第 11 週 | Primate macaque (國防醫學院張廷宇,楊幼屏,陳可欣老師) |
| 第 12 週 | Primate macaque(國防醫學院張廷宇,楊幼屏,陳可欣老師) |
| 第 13 週 | The Pig model(國防醫學院張廷宇,楊幼屏,陳可欣老師) |
| 第 14 週 | Human homo sapiens (神研所張立鴻老師) |
| 第 15 週 | Human homo sapiens (神研所張立鴻老師) |
| 第 16 週 | Final Exam |
Emerging Model Organisms: A Laboratory Manual, Volume 1 Model Organisms: Cambridge University Press, Rachel A. Ankeny, University of Adelaide, Sabina Leonelli, University of Exeter