高等蛋白質體學
Advanced Proteomics
學期
113-2
學分
2
學分
當期課號
132906
永久課號
LSBM30047
開課單位
生化暨分子生物研究所
授課教師
李麗花、蔡有光、吳韋訥、廖辰中
校區
陽明
類別
選修
上課時間表
| 節 | 週一 |
|---|---|
3 10:10–11:00 | 高等蛋白質體學 YL402 2 節連堂 |
4 11:10–12:00 |
* 根據陽明交大上課時間表所列
概述
1. Understand what hypotheses are tested in proteomics studies; 2. Learn what methods and instruments have been used in modern proteomics; 3. Understand how valid the conclusions are in proteomics papers based on the limitations of methodologies; 4. Learn how proteomics technology may enhance your research; 5. Learn how a proteomics project can be schemed and carried out with adequate methodologies.
先修科目
Analytical Chemistry, Organic Chemistry and Biochemistry
評分方式
Midterm: 50% Final: 50%
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | Principle of proteomics data analysis |
| 第 2 週 | Introduction to proteomics |
| 第 3 週 | Protein/proteome sample preparation |
| 第 4 週 | Fundamentals of mass spectrometry |
| 第 5 週 | Ion trap mass spectrometry in proteomics |
| 第 6 週 | Orbitrap mass spectrometry in proteomics |
| 第 7 週 | LC-MS/MS-based protein identification |
| 第 8 週 | Protein modification analyses in proteomics |
| 第 9 週 | Protein complexomics and interactomics |
| 第 10 週 | 期中考 |
| 第 11 週 | Quantitative proteomics |
| 第 12 週 | Examples of proteomics studies |
| 第 13 週 | Clinical proteomics |
| 第 14 週 | MaxQuant tutorial and practice - 1 |
| 第 15 週 | MaxQuant tutorial and practice -2 |
| 第 16 週 | 期末考 |
| 第 17 週 | 自主學習 |
| 第 18 週 | 自主學習 |