癌症幹細胞與標靶治療

Cancer Stem-like Cells and Target

學期

113-2

學分

3 學分

當期課號

430207

永久課號

BTMB30047

開課單位

分子醫學與生物工程研究所

授課教師

邱光裕

校區

博愛

類別

選修

上課時間表

節	週四
5 13:20–14:10	癌症幹細胞與標靶治療 BI311 3 節連堂
6 14:20–15:10
7 15:30–16:20

* 根據陽明交大上課時間表所列

概述

Introducing the concept of cancer stem cells (CSCs) in oncology. Plasticity of cancer stem cells including lineage switches and epigenetic regulation of CSCs. And tumor organoids models in oncological and CSCs researches.

先修科目

Molecular biology Oncology

評分方式

student presentation: 30% assignments: 70%

週次計畫

週次	主題
第 1 週	General introduction
第 2 週	Cancer initiation and classical view of mutation motivated cellular transformations
第 3 週	What is stemness in cancer ?
第 4 週	Hypothesis and discovery of cancer stem cells
第 5 週	What defines cancer stem cells
第 6 週	Genetic mutations and cancer plasticity - a paradigm switch of a view of cancer
第 7 週	Properties of cancer stem cells and the clinical challenges
第 8 週	Tumorigenesis and cellular lineages derived from cancer stem cells
第 9 週	Tumor microenvironments and cancer progressions
第 10 週	Niche microenvironments for stem cells and cancer organoids - Spatial oncology in a dish
第 11 週	Cancer spatial biology
第 12 週	Cancer organoids as modern model system for oncological researches - precision and personalized medicine
第 13 週	Cancer organoids and immunotherapy - in vitro training of anti-cancer immune cells
第 14 週	Gene medicines for cancers -Oncolytic vehicles
第 15 週	Cancer organoids and Biochips
第 16 週	student presentation (optional)
第 17 週	student presentation (optional)
第 18 週	student presentation (optional)

教科書

The Death of Cancer (Publisher ‏ : ‎ Sarah Crichton Books; Reprint edition (November 1, 2016) Authors : DeVita, Vincent T., Jr., M.D./ DeVita-Raeburn, Elizabeth Language ‏ : ‎ English Paperback ‏ : ‎ 336 pages ISBN-10 ‏ : ‎ 0374536481 ISBN-13 ‏ : ‎ 978-0374536480)

Office Hours

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