校際選修

115-1 選課時程

進行中

  • 初選第一階段 6/15/2026
  • 初選第二階段 6/22/2026
  • 校際選修 8/24/2026
  • 初選第三階段 8/31/2026
  • 開學後加退選 9/7/2026
  • 逾期加退選 9/21/2026
選課資源

生物化學

Biochemistry

學期
114-1
學分
4 學分
當期課號
112505
永久課號
LSLS10021
開課單位
生命科學系暨基因體科學研究所
授課教師
孫維欣、張欣暘、陳嘉霖
校區
陽明
類別
必修
上課時間表
週一
週四
3
10:10–11:00
生物化學
YL402
2 節連堂
生物化學
YL402
2 節連堂
4
11:10–12:00

* 根據陽明交大上課時間表所列

概述

課程主旨在介紹細胞內大分子 (醣類、脂質、氨基酸、核苷酸) 的結構及合成與代謝反應與其參與之酵素,除影響大分子功能,亦調控細胞生理功能。合成與代謝反應的缺失常造成許多疾病,故對疾病病理機制的基礎研究、臨床醫療發展應用有助益。包含下列主題: 1. 醣類結構與代謝 2. 脂質結構與代謝 3. 氨基酸結構與代謝 4. 核苷酸結構與代謝 This course aims to introduce structures, function and metabolisms of macromolecules (including carbohydrates, lipid, amino acids and nucleotides). It also covers enzymes involved in the catabolism and the anabolism of macromolecules. The defects in the metabolic pathways are often associated with diseases. Therefore, understanding of the metabolic pathways for macromolecules could be useful for the study of disease pathogenesis and be beneficial for development of clinical therapeutics. Topics: 1. Carbohydrate and Carbohydrate Metabolism 2. lipid and Lipid Metabolism 3. Metabolism of Nitrogenous compounds 4. Nucleotide Metabolism

先修科目

普通生物學、有機化學 Biology, Organic Chemistry

教學方式

Lectures and presentation

評分方式

四次評量 (含筆試、作業、報告), 每次佔25% 4 Written exams/reports/homework, each 25%

週次計畫
週次主題
第 1 週Carbohydrates: Sugars, Saccharides, Glycans (Chap. 9)
第 1 週Carbohydrates: Sugars, Saccharides, Glycans (Chap. 9)
第 2 週Carbohydrates: Sugars, Saccharides, Glycans (Chap. 9) Chemical Logic of Metabolism (Chap. 12)
第 2 週Carbohydrates: Sugars, Saccharides, Glycans (Chap. 9) Chemical Logic of Metabolism (Chap. 12)
第 3 週Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13)
第 3 週Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13)
第 4 週Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13)
第 4 週Carbohydrate Metabolism: Glycolysis, Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway (Chap. 13)
第 5 週Exam 1 (Chapters 9, 12, 13) Citric Acid Cycle and Glyoxylate Cycle (Chap. 14)
第 5 週Exam 1 (Chapters 9, 12, 13) Citric Acid Cycle and Glyoxylate Cycle (Chap. 14)
第 6 週Moon Festival Citric Acid Cycle and Glyoxylate Cycle (Chap. 14)
第 7 週Citric Acid Cycle and Glyoxylate Cycle (Chap. 14) Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15)
第 7 週Citric Acid Cycle and Glyoxylate Cycle (Chap. 14) Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15)
第 8 週Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15)
第 8 週Electron Transport, Oxidative Phosphorylation and Oxygen Metabolism (Chap. 15)
第 9 週Exam 2 (Chapters 14, 15) Lipids (Chap. 10)
第 9 週Exam 2 (Chapters 14, 15) Lipids (Chap. 10)
第 10 週Lipid Metabolism I: Fatty Acids Triacylglycerols and Lipoproteins (Chap. 17)
第 10 週Lipid Metabolism I: Fatty Acids Triacylglycerols and Lipoproteins (Chap. 17)
第 11 週Interorgan and Intracellular coordination of Energy Metabolism in Vertebrate (Chap. 18)
第 11 週Interorgan and Intracellular coordination of Energy Metabolism in Vertebrate (Chap. 18)
第 12 週Lipid Metabolism II: membrane lipids, Steroids, Isoprenoids, and Eicosanoids (Chap. 19)
第 12 週Lipid Metabolism II: membrane lipids, Steroids, Isoprenoids, and Eicosanoids (Chap. 19)
第 13 週Exam 3 (Chapters 10, 17, 18, 19) Metabolism of Nitrogenous compounds I: Principles of Biosynthesis, Utilization, and Turnover (Chap.20)
第 13 週Exam 3 (Chapters 10, 17, 18, 19) Metabolism of Nitrogenous compounds I: Principles of Biosynthesis, Utilization, and Turnover (Chap.20)
第 14 週Metabolism of Nitrogenous compounds I: Principles of Biosynthesis, Utilization, and Turnover (Chap.20) Metabolism of Nitrogenous compounds II: Amino Acids, Porphyrins, and Neurotransmitters (Chap.21)
第 14 週Metabolism of Nitrogenous compounds I: Principles of Biosynthesis, Utilization, and Turnover (Chap.20) Metabolism of Nitrogenous compounds II: Amino Acids, Porphyrins, and Neurotransmitters (Chap.21)
第 15 週Metabolism of Nitrogenous compounds II: Amino Acids, Porphyrins, and Neurotransmitters (Chap.21) Nucleotide Metabolism (Chap.22)
第 15 週Metabolism of Nitrogenous compounds II: Amino Acids, Porphyrins, and Neurotransmitters (Chap.21) Nucleotide Metabolism (Chap.22)
第 16 週Nucleotide Metabolism (Chap.22) Exam 4 (Chapters 20, 21, 22)
第 16 週Nucleotide Metabolism (Chap.22) Exam 4 (Chapters 20, 21, 22)
教科書

Biochemistry (4th. ed.), Mathews, Van Holde, Appling, and Anthony-Cahill 2013

Office Hours
地點
Dr. Sun, Room 708, Library, information, research building
時間
Monday afternoon (14:00-15:00)
聯絡方式
Dr. Sun: weihsin@nycu.edu.tw