計算生物概論
Introduction to Computaional Biology
學期
114-1
學分
2
學分
當期課號
410004
永久課號
BTBT10054
開課單位
生物科技學系
授課教師
朱智瑋、林峻宇
校區
博愛
類別
必修
上課時間表
| 節 | 週五 |
|---|---|
5 13:20–14:10 | 計算生物概論 BI310 2 節連堂 |
6 14:20–15:10 |
* 根據陽明交大上課時間表所列
概述
This course introduces the principles and practices of computational biology. The objective is to develop basic skills and abilities of students to understand the concepts, formulate strategies, and conduct computational biology analysis.
先修科目
Calculus; Chemistry; Physics; Biology 1
評分方式
Homework 30%, midterm 35 %, final 35%
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | Brief introduction of computational biology (Lin) |
| 第 2 週 | Sequence Alignment: Pairwise Sequence Alignment (Lin) |
| 第 3 週 | Sequence Alignment: BLOSUM matrix and PAM scoring matrix (Lin) |
| 第 4 週 | Basic Local Alignment Search Tool (Lin) |
| 第 5 週 | Multiple Sequence Alignment, profile, and motif (Lin) Big data analysis and clustering (Lin) |
| 第 6 週 | National Day (Holiday) |
| 第 7 週 | Gene expression analysis and functional enrichment analysis Network Biology and Medicine (Lin) |
| 第 8 週 | Taiwan Restoration Day (Holiday) |
| 第 9 週 | Midterm exam (Lin) |
| 第 10 週 | Structure alignment (Chu) |
| 第 11 週 | Structure alignment (Chu) |
| 第 12 週 | Molecular mechanics (Chu) |
| 第 13 週 | Molecular mechanics (Chu) |
| 第 14 週 | Molecular mechanics (Chu) |
| 第 15 週 | Molecular mechanics (Chu) |
| 第 16 週 | Final exam |
教科書
1.Lecture notes and supplementary materials provided by the instructors. 2.Reading material: Understanding bioinformatics by Zvelebil and Baum 2008 Garland Science (可於華通訂購).
Office Hours
- 時間
- 朱智瑋 2CD 賢齊館 417 林峻宇 2CD 賢齊館 413
- 聯絡方式
- 林峻宇 chunyulin@nycu.edu.tw 朱智瑋 jwchu@nctu.edu.tw