神經基因學概論
Introduction of neurogenetics
| 節 | 週四 |
|---|---|
N 12:20–13:10 | 神經基因學概論 YR102 |
* 根據陽明交大上課時間表所列
課程概述與目標： 1. 了解基因診斷之技術與判讀 2. 認識常見的神經遺傳疾病與其治病機轉，如Spinocerebellar ataxia, Huntington’s disease, amyotrophic lateral sclerosis, myotonia dystrophy等 3. 了解新穎基因治療技術及其應用 1. Understanding genetic diagnosis and interpretation of genetic tests 2. Common disease-causing mechanism of neurogenetic disorders, such as spinocerebellar ataxia, Huntington’s disease, amyotrophic lateral sclerosis, myotonia dystrophy 3. Novel genetic therapies and their applications
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遺傳性神經疾病表現多元，近年來，相關研究逐漸了解這些疾病的治病機轉，許多看似無關的疾病背後可能有相同的分子機轉。這些疾病的治療也漸露曙光。神經基因學領域結合了分子生物學、遺傳學及神經科學，這堂課將了解神經系統疾病的遺傳機制，為預防、診斷和治療提供基礎。 Hereditary neurological diseases present with diverse manifestations. In recent years, research has gradually uncovered the pathogenic mechanisms underlying these disorders, revealing that many seemingly unrelated diseases may share similar molecular pathways. As a result, promising new treatments are emerging. The field of neurogenetics integrates molecular biology, genetics, and neuroscience. In this course, we will explore the genetic mechanisms of neurological diseases, laying the foundation for their prevention, diagnosis, and treatment.
平時表現30%，期中考試30%，期末考試40% In-class performances 30%, mid-term exam 30%, final exam 40%
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction of neurogenetic disorders |
| 第 2 週 | Advances in genetic diagnosis |
| 第 3 週 | Interpretation and analysis of genetic tests |
| 第 4 週 | Molecular basis of neurogenetic disorders |
| 第 5 週 | Short tandem repeats in neurogenetic diseases |
| 第 6 週 | 校際活動週放假一次 |
| 第 7 週 | Spinocerebellar ataxia |
| 第 8 週 | 期中考 |
| 第 9 週 | Huntington’s disease |
| 第 10 週 | Motor neuron diseases |
| 第 11 週 | Motor neuron diseases |
| 第 12 週 | Genetics in neuromuscular disorders |
| 第 13 週 | Therapies in neurogenetic diseases |
| 第 14 週 | Unmet needs in neurogenetic diseases |
| 第 15 週 | Genetics in common neurological diseases |
| 第 16 週 | 期末考 |
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