粒線體功能異常和人類疾病
Mitochondrial dysfunctions and human diseases
學期
114-2
學分
2
學分
當期課號
140316
永久課號
MDCM30084
開課單位
臨床醫學研究所
授課教師
黎萬君、梁毓津、張瀞文、張壯榮、姜為中、吳肇卿、廖皎君、許翺麟、藍昇輝、張通銘、高茂傑、王志豪、高淑慧
校區
陽明
類別
選修
上課時間表
| 節 | 週三 |
|---|---|
7 15:30–16:20 | 粒線體功能異常和人類疾病 YL405 2 節連堂 |
8 16:30–17:20 |
* 根據陽明交大上課時間表所列
概述
Learning Objectives Describe the normal functions of mitochondria (bioenergetics, metabolism, signaling, apoptosis). Explain how mitochondrial dysfunction contributes to human diseases. Identify genetic and environmental causes of mitochondrial dysfunction. Analyze case studies of diseases linked to mitochondrial dysfunction. Critically evaluate therapeutic approaches targeting mitochondrial health
週次計畫
| 週次 | 主題 |
|---|---|
| 第 1 週 | 課程介紹 |
| 第 2 週 | (調至4/18) Introduction of the lesion and mitochondrial dysfunctions and HBV infection (CHB, HCC) |
| 第 3 週 | Mitochondria in aging |
| 第 4 週 | Mitochondrial in cell death signalling |
| 第 5 週 | Electron transport chain and oxidative phosphorylation (OXPHOS) system |
| 第 6 週 | Mitochondria as Life–Death Gatekeepers |
| 第 7 週 | Introduction of the lesion and mitochondrial dysfunctions and HBV infection (CHB, HCC) |
| 第 8 週 | Mitochondria in neurodegenerative diseases |
| 第 9 週 | Metabolic reprogramming initiated by altered mitochondrial metabolism: clinical implications in metabolic diseases |
| 第 10 週 | Endosymbiotic theory of mitochondria |
| 第 11 週 | Mitochondria in fibrotic diseases |
| 第 12 週 | Mitochondrial quality control |
| 第 13 週 | Mitochondria in cancer |
| 第 14 週 | Mitochondria dynamics and cellular homeostasis |
| 第 15 週 | Mitochondria as major producers of radicals and reactive oxygen species |
| 第 16 週 | 期末報告和討論 |