組織工程
Tissue engineering
| 節 | 週四 |
|---|---|
5 13:20–14:10 | 組織工程 BI311 3 節連堂 |
6 14:20–15:10 | |
7 15:30–16:20 |
* 根據陽明交大上課時間表所列
課程概述: 本課程介紹組織工程的核心概念與技術，內容涵蓋細胞生物學基礎、細胞外基質與細胞–材料交互作用、生物材料設計、支架製備、3D 培養與生物反應器，以及新興的 3D 生物列印與器官晶片技術。同時也探討組織工程在再生醫學、藥物研發、臨床治療與產業應用的最新進展。透過講授、文獻討論與實驗操作，學生將建立跨領域的系統性理解，並認識該領域未來的挑戰與發展趨勢。 課程目標: 1. 建立學生對組織工程基本原理與方法的全面認識。 2. 理解細胞、材料與生長因子在組織再生中的角色。 3. 學習並應用生物材料製備、支架設計與 3D 生物列印等技術。 4. 分析組織工程在臨床、藥物開發與產業轉譯上的實際應用。 5. 培養跨領域整合思維與批判性分析能力，為未來研究或產業發展奠定基礎。 Course Overview This course provides a comprehensive introduction to the fundamental principles and advanced technologies of tissue engineering. Topics include the basics of cell biology, extracellular matrix and cell–material interactions, biomaterials design, scaffold fabrication, 3D culture systems, bioreactors, hydrogels, bio-inks, 3D bioprinting, and organ-on-a-chip platforms. In addition, the course highlights translational aspects such as clinical applications, drug discovery, and industrial practices. Through lectures, literature discussions, and laboratory practice, students will gain a multidisciplinary understanding of tissue engineering and explore future challenges and opportunities in the field. Course Objectives 1. Develop a solid understanding of the fundamental concepts and methods in tissue engineering. 2. Recognize the roles of cells, biomaterials, and signaling molecules in tissue regeneration. 3. Acquire knowledge of scaffold design, biomaterials characterization, and emerging 3D bioprinting technologies. 4. Analyze the translational applications of tissue engineering in medicine, drug discovery, and industry. 5. Cultivate critical thinking and interdisciplinary problem-solving skills for future research and professional development.
先修科目或先備能力：需具備細胞生物學、生物化學與生醫材料的基礎知識，以理解組織工程的相關概念。Basic knowledge of cell biology, biochemistry, and biomaterials is required for understanding tissue engineering concepts.
老師於課堂授課,講述課程內容
期中考及期末考成績平均 期中考筆試 40% 期末報告 40% 作業 20% Grading Policy Midterm Exam (written): 40% Final Report: 40% Assignments: 20%
| 週次 | 主題 |
|---|---|
| 第 1 週 | Introduction to Tissue Engineering 組織工程導論 |
| 第 2 週 | Cell Biology for Tissue Engineering 細胞生物學在組織工程中的應用 |
| 第 3 週 | Extracellular Matrix & Cell–Material Interactions 細胞外基質與細胞–材料交互作用 |
| 第 4 週 | Biomaterials for Tissue Engineering 應用於組織工程的生物材料 |
| 第 5 週 | Scaffold Design & Fabrication 組織工程支架的設計與製備 |
| 第 6 週 | 校際活動週放假 |
| 第 7 週 | Characterization of Biomaterials 生物材料的結構分析和性質鑑定 |
| 第 8 週 | Midterm Exam 期中考 |
| 第 9 週 | Hydrogels and Bio-inks 水凝膠與生物墨水 |
| 第 10 週 | 3D Bioprinting in Tissue Engineering 3D 生物列印於組織工程的應用 |
| 第 11 週 | 3D Culture and Bioreactors 3D 細胞培養技術與生物反應器 |
| 第 12 週 | Laboratory Practice / Experiments 實驗課程 / 操作 |
| 第 13 週 | Organ-on-a-Chip Systems 器官晶片系統 |
| 第 14 週 | Multidisciplinary Applications of Tissue Engineering 組織工程的多領域應用 |
| 第 15 週 | Industry Applications & Startups 產業應用與新創公司 |
| 第 16 週 | Final Exam 期末考 |
老師自製的上課講義 參考Principles of Tissue Engineering 5th Edition 及研究論文等 Instructor-prepared lecture notes, based on Principles of Tissue Engineering, 5th Edition and selected research articles. Textbook: Principles of Tissue Engineering, 5th Edition. Editors: Robert Lanza, Robert Langer, Joseph P. Vacanti, and Anthony Atala. Publisher: Academic Press (Elsevier), 2020.
- 地點
- 賢齊樓 536室
- 時間
- 請email 和教授約面談時間 Please email the professor to schedule a meeting time.
- 聯絡方式
- Email: melodylin@nycu.eud.tw